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Using Public Control Genotype Data to Increase Power and Decrease Cost of Case-Control Genetic Association Studies
Genome-wide association (GWA) studies are a powerful approach for identifying novel genetic risk factors associated with human disease. A GWA study typically requires the inclusion of thousands of samples to have sufficient statistical power to detect single nucleotide polymorphisms (SNPs) that are...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3133924/ https://ncbi.nlm.nih.gov/pubmed/20821337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-010-0880-x |
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