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LRTae: improving statistical power for genetic association with case/control data when phenotype and/or genotype misclassification errors are present

BACKGROUND: In the field of statistical genetics, phenotype and genotype misclassification errors can substantially reduce power to detect association with genetic case/control studies. Misclassification also can bias population frequency parameters such as genotype, haplotype, or multi-locus genoty...

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Detalhes bibliográficos
Main Authors: Barral, Sandra, Haynes, Chad, Stone, Millicent, Gordon, Derek
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1471798/
https://ncbi.nlm.nih.gov/pubmed/16689984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-7-24
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