Effects of Bolus Injection of 5-Fluorouracil on Steady-State Plasma Concentrations of 5-Fluorouracil in Japanese Patients with Advanced Colorectal Cancer

Objectives: The irinotecan (CPT-11) + 5-fluorouracil (5-FU)/leucovorin (LV) + UFT/LV chemotherapy, in which repetitive oral administration of UFT/LV replaces the infusion of 5-FU/LV in the FOLFIRI regimen, has been proposed previously. In this study, five of 10 patients were injected with a bolus of...

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Bibliografiske detaljer
Main Authors: Tamura, Takao, Kuwahara, Akiko, Kadoyama, Kaori, Yamamori, Motohiro, Nishiguchi, Kohshi, Inokuma, Tsubasa, Takemoto, Yoshiji, Chayahara, Naoko, Okuno, Tatsuya, Miki, Ikuya, Fujishima, Yoshimi, Sakaeda, Toshiyuki
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2011
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133846/
https://ncbi.nlm.nih.gov/pubmed/21750645
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