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Exploration of the relationship between topology and designability of conformations

Protein structures are evolutionarily more conserved than sequences, and sequences with very low sequence identity frequently share the same fold. This leads to the concept of protein designability. Some folds are more designable and lots of sequences can assume that fold. Elucidating the relationsh...

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Bibliografiske detaljer
Main Authors: Leelananda, Sumudu P., Towfic, Fadi, Jernigan, Robert L., Kloczkowski, Andrzej
Format: Artigo
Sprog:Inglês
Udgivet: American Institute of Physics 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133807/
https://ncbi.nlm.nih.gov/pubmed/21702580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3596947
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