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Pharmacogenetics and breast cancer endocrine therapy: CYP2D6 as a predictive factor for tamoxifen metabolism and drug response?

The identification of genetic polymorphisms that influence the efficacy and safety of therapies for breast cancer may allow future treatments to be individualised based not only on tumour characteristics but also on host genetics. Genetic factors that affect the metabolism, efficacy and safety of ta...

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Autors principals: Stearns, Vered, Rae, James M.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133663/
https://ncbi.nlm.nih.gov/pubmed/19019258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S1462399408000896
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