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Pharmacogenetics and breast cancer endocrine therapy: CYP2D6 as a predictive factor for tamoxifen metabolism and drug response?

The identification of genetic polymorphisms that influence the efficacy and safety of therapies for breast cancer may allow future treatments to be individualised based not only on tumour characteristics but also on host genetics. Genetic factors that affect the metabolism, efficacy and safety of ta...

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Detalhes bibliográficos
Main Authors: Stearns, Vered, Rae, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133663/
https://ncbi.nlm.nih.gov/pubmed/19019258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S1462399408000896
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