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Electrophilic Components of Diesel Exhaust Particles (DEP) Activate Transient Receptor Potential Ankyrin-1 (TRPA1): A Probable Mechanism of Acute Pulmonary Toxicity for DEP

Inhalation of environmental particulate matter (PM) is correlated with adverse health effects in humans, but gene products that couple detection with cellular responses, and the specific properties of PM that target different pathways, have not been fully elucidated. TRPA1 and V1 are two cation chan...

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Detalhes bibliográficos
Main Authors: Deering-Rice, Cassandra E., Romero, Erin G., Shapiro, Darien, Hughen, Ronald W., Light, Alan R., Yost, Garold S., Veranth, John M., Reilly, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133601/
https://ncbi.nlm.nih.gov/pubmed/21591660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx200123z
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