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Offspring of Mothers Fed a High Fat Diet Display Hepatic Cell Cycle Inhibition and Associated Changes in Gene Expression and DNA Methylation

The association between an adverse early life environment and increased susceptibility to later-life metabolic disorders such as obesity, type 2 diabetes and cardiovascular disease is described by the developmental origins of health and disease hypothesis. Employing a rat model of maternal high fat...

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Detalhes bibliográficos
Main Authors: Dudley, Kevin J., Sloboda, Deborah M., Connor, Kristin L., Beltrand, Jacques, Vickers, Mark H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133558/
https://ncbi.nlm.nih.gov/pubmed/21779332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021662
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