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Overweight and CpG methylation of the Pomc promoter in offspring of high-fat-diet-fed dams are not “reprogrammed” by regular chow diet in rats

This study aimed to determine whether epigenetic malprogramming induced by high-fat diet (HFD) has an obesogenic effect on nonmated and mated female rats and their offspring. Further, it aimed to reprogram offspring's epigenetic malprogramming and phenotype by providing normal diet after weanin...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Marco, Asaf, Kisliouk, Tatiana, Tabachnik, Tzlil, Meiri, Noam, Weller, Aron
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395737/
https://ncbi.nlm.nih.gov/pubmed/24928196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-255620
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