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A Functional Role for Nlrp6 in Intestinal Inflammation and Tumorigenesis

The Nod-like receptor (NLR) family member, Nlrp6, has been implicated in inflammasome signaling to activate caspase-1, which is essential for the production of mature IL-1β and IL-18. However, a function for Nlrp6 in vivo has never been demonstrated. Due to the relative high expression of Nlrp6 in i...

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Bibliografiset tiedot
Päätekijät: Chen, Grace Y., Liu, Maochang, Wang, Fuyuan, Bertin, John, Núñez, Gabriel
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133458/
https://ncbi.nlm.nih.gov/pubmed/21543645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100412
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