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A Functional Role for Nlrp6 in Intestinal Inflammation and Tumorigenesis
The Nod-like receptor (NLR) family member, Nlrp6, has been implicated in inflammasome signaling to activate caspase-1, which is essential for the production of mature IL-1β and IL-18. However, a function for Nlrp6 in vivo has never been demonstrated. Due to the relative high expression of Nlrp6 in i...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3133458/ https://ncbi.nlm.nih.gov/pubmed/21543645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100412 |
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