Modulation of human β-defensin-1 (hBD-1) in plasmacytoid dendritic cells (PDC), monocytes, and epithelial cells by influenza virus, Herpes simplex virus, and Sendai virus and its possible role in innate immunity

hBD comprise a family of antimicrobial peptides that plays a role in bridging the innate and adaptive immune responses to infection. The expression of hBD-2 increases upon stimulation of numerous cell types with LPS and proinflammatory cytokines. In contrast, hBD-1 remains constitutively expressed i...

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Bibliographische Detailangaben
Hauptverfasser: Ryan, Lisa K., Dai, Jihong, Yin, Zhiwei, Megjugorac, Nicholas, Uhlhorn, Victoria, Yim, Sunghan, Schwartz, Kyell D., Abrahams, Joshua M., Diamond, Gill, Fitzgerald-Bocarsly, Patricia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Leukocyte Biology 2011
Schlagworte:
Host Defense & Pathophysiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133436/
https://ncbi.nlm.nih.gov/pubmed/21551252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0209079
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