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Squamous Cell Carcinoma Antigen 1 Promotes Caspase-8-Mediated Apoptosis in Response to Endoplasmic Reticulum Stress While Inhibiting Necrosis Induced by Lysosomal Injury

Squamous cell carcinoma antigen 1 (SCCA1) is a member of the serine protease inhibitor (serpin) family of proteins, whose target proteases include the cathepsins. Initially identified as a serological marker for advanced squamous cell carcinomas of the cervix, SCCA1 has also been found to be associa...

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Bibliographic Details
Main Authors: Ullman, Erica, Pan, Ji-An, Zong, Wei-Xing
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133401/
https://ncbi.nlm.nih.gov/pubmed/21576355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05452-11
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