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PEST Motif Serine and Tyrosine Phosphorylation Controls Vascular Endothelial Growth Factor Receptor 2 Stability and Downregulation

The internalization and degradation of vascular endothelial growth factor receptor 2 (VEGFR-2), a potent angiogenic receptor tyrosine kinase, is a central mechanism for the regulation of the coordinated action of VEGF in angiogenesis. Here, we show that VEGFR-2 is ubiquitinated in response to VEGF,...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Meyer, Rosana D., Srinivasan, Srimathi, Singh, Amrik J., Mahoney, John E., Gharahassanlou, Kobra Rezazadeh, Rahimi, Nader
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133358/
https://ncbi.nlm.nih.gov/pubmed/21402774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01006-10
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