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Functional Significance of an Evolutionarily Conserved Alanine (GCA) Resume Codon in tmRNA in Escherichia coli

Occasionally, ribosomes stall on mRNAs prior to the completion of the polypeptide chain. In Escherichia coli and other eubacteria, tmRNA-mediated trans-translation is a major mechanism that recycles the stalled ribosomes. The tmRNA possesses a tRNA-like domain and a short mRNA region encoding a shor...

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Detalhes bibliográficos
Main Authors: Kapoor, Suman, Samhita, Laasya, Varshney, Umesh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133319/
https://ncbi.nlm.nih.gov/pubmed/21602351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01446-10
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