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Acetylation of a Conserved Lysine Residue in the ATP Binding Pocket of p38 Augments Its Kinase Activity during Hypertrophy of Cardiomyocytes

Like phosphorylation, acetylation of lysine residues within a protein is considered a biologically relevant modification that controls the activity of target proteins. During stress of cells, massive protein acetylation takes place. Here, we show that p38 mitogen-activated protein kinase (MAPK), whi...

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Hlavní autoři: Pillai, Vinodkumar B., Sundaresan, Nagalingam R., Samant, Sadhana A., Wolfgeher, Don, Trivedi, Chinmay M., Gupta, Mahesh P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133249/
https://ncbi.nlm.nih.gov/pubmed/21444723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01205-10
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