Pathological Signaling via Platelet-Derived Growth Factor Receptor α Involves Chronic Activation of Akt and Suppression of p53

Eitemau Tebyg

• A Reactive Oxygen Species-Mediated, Self-Perpetuating Loop Persistently Activates Platelet-Derived Growth Factor Receptor α
  gan: Lei, Hetian, et al.
  Cyhoeddwyd: (2014)
• Focus on Molecules: Platelet-derived Growth Factor C, PDGF-C
  gan: Lei, Hetian, et al.
  Cyhoeddwyd: (2007)
• RasGAP Promotes Autophagy and Thereby Suppresses Platelet-Derived Growth Factor Receptor-Mediated Signaling Events, Cellular Responses, and Pathology
  gan: Lei, Hetian, et al.
  Cyhoeddwyd: (2015)
• Growth Factors Outside of the Platelet-derived Growth Factor (PDGF) Family Employ Reactive Oxygen Species/Src Family Kinases to Activate PDGF Receptor α and Thereby Promote Proliferation and Survival of Cells
  gan: Lei, Hetian, et al.
  Cyhoeddwyd: (2009)
• Expression of PDGFRα Is a Determinant of the PVR Potential of ARPE19 Cells
  gan: Lei, Hetian, et al.
  Cyhoeddwyd: (2011)