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Simulation of Chaperonin Effect on Protein Folding: A Shift from Nucleation–Condensation to Framework Mechanism
[Image: see text] The iterative annealing mechanism (IAM) of chaperonin-assisted protein folding is explored in a framework of a well-established coarse-grained protein modeling tool, which enables the study of protein dynamics in a time-scale well beyond classical all-atom molecular mechanics. The...
שמור ב:
| Main Authors: | , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Chemical Society
2011
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| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3132998/ https://ncbi.nlm.nih.gov/pubmed/21618995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja203275f |
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