Vascular Endothelial Growth Factor Blockade Promotes the Transition From Compensatory Cardiac Hypertrophy to Failure in Response to Pressure Overload

Cardiac hypertrophy is associated with upregulation of vascular endothelial growth factor (VEGF) in the myocardium. Here, we evaluated the effects of a decoy VEGF receptor on heart morphology and function to a murine model of pressure overload hypertrophy. Mice were administered adenoviral vector en...

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Bibliographic Details
Main Authors: Izumiya, Yasuhiro, Shiojima, Ichiro, Sato, Kaori, Sawyer, Douglas B., Colucci, Wilson S., Walsh, Kenneth
Format: Artigo
Language:Inglês
Published: 2006
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132898/
https://ncbi.nlm.nih.gov/pubmed/16567591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.HYP.0000215207.54689.31
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