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Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis
Chromosomal instability is a major pathway of sporadic colon carcinogenesis. Chromosome arm 1p appears to be one of the “hot spots” in the non-neoplastic mucosa that, when deleted, is associated with the initiation of carcinogenesis. Chromosome arm 1p contains genes associated with DNA repair, spind...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Dove Medical Press
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3132853/ https://ncbi.nlm.nih.gov/pubmed/21753893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CEG.S17114 |
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