Nfatc1 Coordinates Valve Endocardial Cell Lineage Development Required for Heart Valve Formation

RATIONALE: Formation of heart valves requires early endocardial to mesenchymal transformation (EMT) to generate valve mesenchyme and subsequent endocardial cell proliferation to elongate valve leaflets. Nfatc1 (nuclear factor of activated T cells, cytoplasmic 1) is highly expressed in valve endocard...

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Bibliografiske detaljer
Main Authors: Wu, Bingruo, Wang, Yidong, Lui, Wendy, Langworthy, Melissa, Tompkins, Kevin L., Hatzopoulos, Antonis K., Baldwin, H. Scott, Zhou, Bin
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132827/
https://ncbi.nlm.nih.gov/pubmed/21597012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.111.245035
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