BMP2 expression in the endocardial lineage is required for AV endocardial cushion maturation and remodeling

Distal outgrowth, maturation and remodeling of the endocardial cushion mesenchyme in the atrioventricular (AV) canal are the essential morphogenetic events during four-chambered heart formation. Mesenchymalized AV endocardial cushions give rise to the AV valves and the membranous ventricular septum...

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Udgivet i:Dev Biol
Main Authors: Saxon, Jacob G., Baer, Daniel R., Barton, Julie A., Hawkins, Travis, Wu, Bingruo, Trusk, Thomas C., Harris, Stephen E., Zhou, Bin, Mishina, Yuji, Sugi, Yukiko
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948002/
https://ncbi.nlm.nih.gov/pubmed/28790014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2017.08.008
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