Increased cerebral (R)-[(11)C]PK11195 uptake and glutamate release in a rat model of traumatic brain injury: a longitudinal pilot study

BACKGROUND: The aim of the present study was to investigate microglia activation over time following traumatic brain injury (TBI) and to relate these findings to glutamate release. PROCEDURES: Sequential dynamic (R)-[(11)C]PK11195 PET scans were performed in rats 24 hours before (baseline), and one...

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Détails bibliographiques
Auteurs principaux: Folkersma, Hedy, Foster Dingley, Jessica C, van Berckel, Bart NM, Rozemuller, Annemieke, Boellaard, Ronald, Huisman, Marc C, Lammertsma, Adriaan A, Vandertop, W Peter, Molthoff, Carla FM
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2011
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132713/
https://ncbi.nlm.nih.gov/pubmed/21672189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-67
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