Increased cerebral (R)-[(11)C]PK11195 uptake and glutamate release in a rat model of traumatic brain injury: a longitudinal pilot study

BACKGROUND: The aim of the present study was to investigate microglia activation over time following traumatic brain injury (TBI) and to relate these findings to glutamate release. PROCEDURES: Sequential dynamic (R)-[(11)C]PK11195 PET scans were performed in rats 24 hours before (baseline), and one...

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Detalhes bibliográficos
Main Authors: Folkersma, Hedy, Foster Dingley, Jessica C, van Berckel, Bart NM, Rozemuller, Annemieke, Boellaard, Ronald, Huisman, Marc C, Lammertsma, Adriaan A, Vandertop, W Peter, Molthoff, Carla FM
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132713/
https://ncbi.nlm.nih.gov/pubmed/21672189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-67
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