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Tonic Modulation of Spinal Hyperexcitability by the Endocannabinoid Receptor System in a Rat Model of Osteoarthritis Pain

OBJECTIVE: To investigate the impact of an experimental model of osteoarthritis (OA) on spinal nociceptive processing and the role of the inhibitory endocannabinoid system in regulating sensory processing at the spinal level. METHODS: Experimental OA was induced in rats by intraarticular injection o...

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Dettagli Bibliografici
Autori principali: Sagar, Devi Rani, Staniaszek, Lydia E, Okine, Bright N, Woodhams, Stephen, Norris, Leonie M, Pearson, Richard G, Garle, Michael J, Alexander, Stephen P H, Bennett, Andrew J, Barrett, David A, Kendall, David A, Scammell, Brigitte E, Chapman, Victoria
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley Subscription Services, Inc., A Wiley Company 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132591/
https://ncbi.nlm.nih.gov/pubmed/20722027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27698
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