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Dominant Cx26 mutants associated with hearing loss have dominant-negative effects on wild type Cx26
Mutations in GJB2, the gene encoding the human gap junction protein connexin26 (Cx26), cause either non-syndromic hearing loss or syndromes affecting both hearing and skin. We have investigated whether dominant Cx26 mutants can interact physically with wild type Cx26. HeLa cells stably expressing wi...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3132585/ https://ncbi.nlm.nih.gov/pubmed/21040787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2010.10.002 |
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