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Dominant Cx26 mutants associated with hearing loss have dominant-negative effects on wild type Cx26

Mutations in GJB2, the gene encoding the human gap junction protein connexin26 (Cx26), cause either non-syndromic hearing loss or syndromes affecting both hearing and skin. We have investigated whether dominant Cx26 mutants can interact physically with wild type Cx26. HeLa cells stably expressing wi...

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Detalhes bibliográficos
Main Authors: Zhang, Junxian, Scherer, Steven S., Yum, Sabrina W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132585/
https://ncbi.nlm.nih.gov/pubmed/21040787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2010.10.002
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