Ring1B Compacts Chromatin Structure and Represses Gene Expression Independent of Histone Ubiquitination

How polycomb group proteins repress gene expression in vivo is not known. While histone-modifying activities of the polycomb repressive complexes (PRCs) have been studied extensively, in vitro data have suggested a direct activity of the PRC1 complex in compacting chromatin. Here, we investigate hig...

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Main Authors: Eskeland, Ragnhild, Leeb, Martin, Grimes, Graeme R., Kress, Clémence, Boyle, Shelagh, Sproul, Duncan, Gilbert, Nick, Fan, Yuhong, Skoultchi, Arthur I., Wutz, Anton, Bickmore, Wendy A.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132514/
https://ncbi.nlm.nih.gov/pubmed/20471950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.02.032
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