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Ring1B Compacts Chromatin Structure and Represses Gene Expression Independent of Histone Ubiquitination
How polycomb group proteins repress gene expression in vivo is not known. While histone-modifying activities of the polycomb repressive complexes (PRCs) have been studied extensively, in vitro data have suggested a direct activity of the PRC1 complex in compacting chromatin. Here, we investigate hig...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3132514/ https://ncbi.nlm.nih.gov/pubmed/20471950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.02.032 |
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