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Failure of pertussis toxin to inhibit activation of guanylate cyclase by the heat-stable enterotoxin of Escherichia coli (STa) in the T84 cell line.

The heat-stable enterotoxin (STa) of Escherichia coli causes intestinal secretion by stimulating guanylate cyclase, an enzyme believed to be distinct from the STa receptor. Pertussis toxin (PT) has been reported to block the ability of STa to stimulate guanylate cyclase in rat intestinal mucosa (S....

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Detalles Bibliográficos
Publicado en:Infect Immun
Main Authors: Crane, J K, Hewlett, E L, Weikel, C S
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1989
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313249/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2564375/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.57.4.1186-1191.1989
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