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Failure of pertussis toxin to inhibit activation of guanylate cyclase by the heat-stable enterotoxin of Escherichia coli (STa) in the T84 cell line.

The heat-stable enterotoxin (STa) of Escherichia coli causes intestinal secretion by stimulating guanylate cyclase, an enzyme believed to be distinct from the STa receptor. Pertussis toxin (PT) has been reported to block the ability of STa to stimulate guanylate cyclase in rat intestinal mucosa (S....

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Crane, J K, Hewlett, E L, Weikel, C S
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1989
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313249/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2564375/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.57.4.1186-1191.1989
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