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Chromosome-wide DNA methylation analysis predicts human tissue-specific X inactivation

X-chromosome inactivation (XCI) results in the differential marking of the active and inactive X with epigenetic modifications including DNA methylation. Consistent with the previous studies showing that CpG island-containing promoters of genes subject to XCI are approximately 50% methylated in fema...

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Autori principali: Cotton, Allison M., Lam, Lucia, Affleck, Joslynn G., Wilson, Ian M., Peñaherrera, Maria S., McFadden, Deborah E., Kobor, Michael S., Lam, Wan L., Robinson, Wendy P., Brown, Carolyn J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer-Verlag 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132437/
https://ncbi.nlm.nih.gov/pubmed/21597963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-011-1007-8
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