Spread of X-chromosome inactivation into autosomal sequences: role for DNA elements, chromatin features and chromosomal domains

X-chromosome inactivation results in dosage equivalence between the X chromosome in males and females; however, over 15% of human X-linked genes escape silencing and these genes are enriched on the evolutionarily younger short arm of the X chromosome. The spread of inactivation onto translocated aut...

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Main Authors: Cotton, Allison M., Chen, Chih-Yu, Lam, Lucia L., Wasserman, Wyeth W., Kobor, Michael S., Brown, Carolyn J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2014
Ábhair:
Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051349/
https://ncbi.nlm.nih.gov/pubmed/24158853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt513
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