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The X-inactivation trans-activator Rnf12 is negatively regulated by pluripotency factors in embryonic stem cells

X-inactivation, the molecular mechanism enabling dosage compensation in mammals, is tightly controlled during mouse early embryogenesis. In the morula, X-inactivation is imprinted with exclusive silencing of the paternally inherited X-chromosome. In contrast, in the post-implantation epiblast, X-ina...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Navarro, Pablo, Moffat, Michael, Mullin, Nicholas P., Chambers, Ian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer-Verlag 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132432/
https://ncbi.nlm.nih.gov/pubmed/21544581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-011-0998-5
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