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The X-inactivation trans-activator Rnf12 is negatively regulated by pluripotency factors in embryonic stem cells
X-inactivation, the molecular mechanism enabling dosage compensation in mammals, is tightly controlled during mouse early embryogenesis. In the morula, X-inactivation is imprinted with exclusive silencing of the paternally inherited X-chromosome. In contrast, in the post-implantation epiblast, X-ina...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer-Verlag
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3132432/ https://ncbi.nlm.nih.gov/pubmed/21544581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-011-0998-5 |
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