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Regulation of Circulating Sclerostin Levels by Sex Steroids in Women and in Men

Sex steroids are important regulators of bone turnover, but the mechanisms of their effects on bone remain unclear. Sclerostin is an inhibitor of Wnt signaling, and circulating estrogen (E) levels are inversely associated with sclerostin levels in postmenopausal women. To directly test for sex stero...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mödder, Ulrike IL, Clowes, Jackie A, Hoey, Kelley, Peterson, James M, McCready, Louise, Oursler, Merry Jo, Riggs, B Lawrence, Khosla, Sundeep
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley Subscription Services, Inc., A Wiley Company 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132405/
https://ncbi.nlm.nih.gov/pubmed/20499362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.128
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