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Transforming growth factor-β1 Suppression of Endotoxin-induced Heme Oxygenase-1 in Macrophages Involves Activation of Smad2 and Downregulation of Ets-2

Heme oxygenase (HO)-1 is a cytoprotective molecule that is induced during the response to injury. An increase in HO-1 is an acute indicator of inflammation, and early induction of HO-1 has been suggested to correlate with severity of injury. While a great deal is known about the induction of HO-1 by...

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Détails bibliographiques
Auteurs principaux: Chung, Su Wol, Kwon, Min-Young, Kang, Young-Ho, Chung, Hun-Taeg, Lee, Seon-Jin, Kim, Hong Pyo, Perrella, Mark A.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132305/
https://ncbi.nlm.nih.gov/pubmed/21437904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22741
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