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Transforming growth factor-β1 Suppression of Endotoxin-induced Heme Oxygenase-1 in Macrophages Involves Activation of Smad2 and Downregulation of Ets-2
Heme oxygenase (HO)-1 is a cytoprotective molecule that is induced during the response to injury. An increase in HO-1 is an acute indicator of inflammation, and early induction of HO-1 has been suggested to correlate with severity of injury. While a great deal is known about the induction of HO-1 by...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3132305/ https://ncbi.nlm.nih.gov/pubmed/21437904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22741 |
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