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Gold Nanorod-siRNA Induces Efficient In Vivo Gene Silencing in the Rat Hippocampus
Gold nanorods (GNRs), cellular imaging nanoprobes, have been used for drug delivery therapy to immunologically privileged regions in the brain. We demonstrate that nanoplexes formed by electrostatic binding between negatively charged RNA and positively charged GNRs, silence the expression of the tar...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3132138/ https://ncbi.nlm.nih.gov/pubmed/21718174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm.11.20 |
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