TLR7 single-nucleotide polymorphisms in the 3' untranslated region and intron 2 independently contribute to systemic lupus erythematosus in Japanese women: a case-control association study

INTRODUCTION: The Toll-like receptor 7 (TLR7) gene, encoded on human chromosome Xp22.3, is crucial for type I interferon production. A recent multicenter study in East Asian populations, comprising Chinese, Korean and Japanese participants, identified an association of a TLR7 single-nucleotide polym...

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Detalhes bibliográficos
Main Authors: Kawasaki, Aya, Furukawa, Hiroshi, Kondo, Yuya, Ito, Satoshi, Hayashi, Taichi, Kusaoi, Makio, Matsumoto, Isao, Tohma, Shigeto, Takasaki, Yoshinari, Hashimoto, Hiroshi, Sumida, Takayuki, Tsuchiya, Naoyuki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132023/
https://ncbi.nlm.nih.gov/pubmed/21396113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3277
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