Association of Functional Polymorphisms in Interferon Regulatory Factor 2 (IRF2) with Susceptibility to Systemic Lupus Erythematosus: A Case-Control Association Study

Interferon regulatory factor 2 (IRF2) negatively regulates type I interferon (IFN) responses, while it plays a role in induction of Th1 differentiation. Previous linkage and association studies in European-American populations suggested genetic role of IRF2 in systemic lupus erythematosus (SLE); how...

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Main Authors: Kawasaki, Aya, Furukawa, Hiroshi, Nishida, Nao, Warabi, Eiji, Kondo, Yuya, Ito, Satoshi, Matsumoto, Isao, Kusaoi, Makio, Amano, Hirofumi, Suda, Akiko, Nagaoka, Shouhei, Setoguchi, Keigo, Nagai, Tatsuo, Hirohata, Shunsei, Shimada, Kota, Sugii, Shoji, Okamoto, Akira, Chiba, Noriyuki, Suematsu, Eiichi, Ohno, Shigeru, Katayama, Masao, Okamoto, Akiko, Kono, Hajime, Tokunaga, Katsushi, Takasaki, Yoshinari, Hashimoto, Hiroshi, Sumida, Takayuki, Tohma, Shigeto, Tsuchiya, Naoyuki
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186848/
https://ncbi.nlm.nih.gov/pubmed/25285625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109764
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