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Regulation of autophagic activity by 14-3-3ζ proteins associated with class III phosphatidylinositol-3-kinase

14-3-3s are binding proteins with survival functions in cells by interaction with proteins involved in the regulation of cell fate. The role of 14-3-3 during autophagy was investigated, thus, a forced expression of 14-3-3ζ reduces C2-ceramide-induced autophagy, whereas depletion of 14-3-3ζ promotes...

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Autor principal: Pozuelo-Rubio, M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132006/
https://ncbi.nlm.nih.gov/pubmed/20885446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.118
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