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Amyotrophic lateral sclerosis and frontotemporal lobar degeneration: A spectrum of TDP-43 proteinopathies

It is now established that pathological transactive response DNA-binding protein with a Mr of 43 kD (TDP-43) on sodium dodecyl sulfate-polyacrylamide gel electrophoresis is the major disease protein in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) with ubiquitin-po...

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Autori principali: Geser, Felix, Lee, Virginia M.-Y., Trojanowski, John Q.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131978/
https://ncbi.nlm.nih.gov/pubmed/20102519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1440-1789.2009.01091.x
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