p75 neurotrophin receptor mediates apoptosis in transit-amplifying cells and its overexpression restores cell death in psoriatic keratinocytes

p75 neurotrophin receptor (p75NTR) belongs to the TNF-receptor superfamily and signals apoptosis in many cell settings. In human epidermis, p75NTR is mostly confined to the transit-amplifying (TA) sub-population of basal keratinocytes. Brain-derived neurotrophic factor (BDNF) or neurotrophin-4 (NT-4...

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Detalhes bibliográficos
Main Authors: Truzzi, F, Marconi, A, Atzei, P, Panza, M C, Lotti, R, Dallaglio, K, Tiberio, R, Palazzo, E, Vaschieri, C, Pincelli, C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131939/
https://ncbi.nlm.nih.gov/pubmed/21151024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.162
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