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NER and HR pathways act sequentially to promote UV-C-induced germ cell apoptosis in Caenorhabditis elegans

Ultraviolet (UV) radiation-induced DNA damage evokes a complex network of molecular responses, which culminate in DNA repair, cell cycle arrest and apoptosis. Here, we provide an in-depth characterization of the molecular pathway that mediates UV-C-induced apoptosis of meiotic germ cells in the nema...

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Detalhes bibliográficos
Main Authors: Stergiou, L, Eberhard, R, Doukoumetzidis, K, Hengartner, M O
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131928/
https://ncbi.nlm.nih.gov/pubmed/21151025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.158
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