Involvement of NF-κB/miR-448 regulatory feedback loop in chemotherapy-induced epithelial–mesenchymal transition of breast cancer cells

The epithelial–mesenchymal transition (EMT) induced by chemotherapeutic agents promotes malignant tumor progression; however, the mechanism underlying the drug-induced EMT remains unclear. In this study, we reported that miR-448 is the most downregulated microRNA following chemotherapy. Suppression...

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Bibliografiske detaljer
Main Authors: Li, Q-Q, Chen, Z-Q, Cao, X-X, Xu, J-D, Xu, J-W, Chen, Y-Y, Wang, W-J, Chen, Q, Tang, F, Liu, X-P, Xu, Z-D
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131865/
https://ncbi.nlm.nih.gov/pubmed/20798686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.103
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