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Inhibition of glycosphingolipid biosynthesis induces cytokinesis failure

Although cells undergo dramatic shape changes during cytokinesis, the role of the plasma membrane and lipids is poorly understood. We report that inactivation of glucosyl ceramide synthase (GCS), either by RNAi or with the small molecule PPMP, causes failure of cleavage furrow ingression. Using mass...

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Bibliografski detalji
Glavni autori: Atilla-Gokcumen, G. E., Bedigian, A. V., Sasse, S., Eggert, U. S.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131740/
https://ncbi.nlm.nih.gov/pubmed/21668028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja202804b
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