Systematic Approaches towards the Development of Host-Directed Antiviral Therapeutics

Since the onset of antiviral therapy, viral resistance has compromised the clinical value of small-molecule drugs targeting pathogen components. As intracellular parasites, viruses complete their life cycle by hijacking a multitude of host-factors. Aiming at the latter rather than the pathogen direc...

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Bibliographic Details
Main Authors: Prussia, Andrew, Thepchatri, Pahk, Snyder, James P., Plemper, Richard K.
Format: Artigo
Language:Inglês
Published: Molecular Diversity Preservation International (MDPI) 2011
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131607/
https://ncbi.nlm.nih.gov/pubmed/21747723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms12064027
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