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Measles virus entry inhibitors: A structural proposal for mechanism of action and the development of resistance()

Previously, we developed a panel of nonpeptidic compounds specifically preventing fusion of the measles virus (MV) with target cells at IC(50) values of 0.6–3 μM. Mutations in the MV fusion protein (MV F) that render resistance to these blockers were described. The structural basis for both inhibiti...

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Autori principali: Prussia, Andrew J., Plemper, Richard K., Snyder, James P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084900/
https://ncbi.nlm.nih.gov/pubmed/19035834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801513p
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