Genetic Reduction of Insulin-like Growth Factor-1 Mimics the Anticancer Effects of Calorie Restriction on Cyclooxygenase-2–Driven Pancreatic Neoplasia

Risk of pancreatic cancer, the fourth deadliest cancer in the U.S., is increased by obesity. Calorie restriction (CR) prevents obesity, suppresses carcinogenesis in many models, and reduces serum levels of insulin-like growth factor (IGF)-1. In the present study, we examined the impact of CR on a mo...

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Detaylı Bibliyografya
Asıl Yazarlar: Lashinger, Laura M., Malone, Lauren M., McArthur, Mark J., Goldberg, Jason A., Daniels, Elizabeth A., Pavone, Amy, Colby, Jennifer K., Smith, Nicole C., Perkins, Susan N., Fischer, Susan M., Hursting, Stephen D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131443/
https://ncbi.nlm.nih.gov/pubmed/21593196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-11-0027
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