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Membrane fusion by the GTPase atlastin requires a conserved C-terminal cytoplasmic tail and dimerization through the middle domain

The biogenesis and maintenance of the endoplasmic reticulum (ER) requires membrane fusion. ER homotypic fusion is driven by the large GTPase atlastin. Domain analysis of atlastin shows that a conserved region of the C-terminal cytoplasmic tail is absolutely required for fusion activity. Atlastin in...

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Bibliografiske detaljer
Main Authors: Moss, Tyler J., Andreazza, Camilla, Verma, Avani, Daga, Andrea, McNew, James A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131361/
https://ncbi.nlm.nih.gov/pubmed/21690399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105056108
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